ABSTRACT
Focal segmental glomerulosclerosis [FSGS] is not an infrequent cause of nephrotic syndrome in the young. The incidence is 5-15 percent. Renal morbidity is significant and the disease relentlessly progresses to renal failure. Failure due to steroid unresponsiveness and resistance to cytotoxic drug regimen necessitates renal transplantation. However, recurrence of the primary disease [FSGS] in the allograft poses a serious problem to the graft survival. We report a case of FSGS that recurred in the graft four months post transplantation in a sixteen year old Bahraini Female
Subject(s)
Humans , Female , Kidney Transplantation , Recurrence , Transplantation, Heterologous , Nephrotic Syndrome , Renal Insufficiency/surgeryABSTRACT
A 42- year-old Bahraini male, known case of scleroderma, underwent renal transplant for persistent renal dys function demanding frequent haemodialysis. The procedure was carried out using live related donor following HLA and cross match. Unilateral nephrectomy was also done in view of long-term intractable hypertension. Histopathology of the diseased kidney confirmed the renovascular changes consistent with scleroderma. Nearly six months following successful transplantation, the patient showed moderate renal dysfunction with hypertension. The allograft biopsy revealed no signs of acute or chronic rejection, but vascular changes of hypertension were evident and also subintimal edema in a medium sized artery, raising the possibility of early changes of scleroderma. The pathology on the allograft biopsy is discussed based on the previous experience on similar cases though scant in the literature
Subject(s)
Humans , Male , Kidney Transplantation , Kidney/pathology , ReviewABSTRACT
We are presenting a young man with Acquired immune Deficiency syndrome [AIDS] who suffered from thrombocytopenic purpura and probable cerebral bleeding. His clinical picture and investigations are discussed
Subject(s)
ThrombocytopeniaABSTRACT
A first case of Waldenstrom' s Macroglobulinaemia is reported from Bahrain and its clinical, hematological and biochemical differentiation from other conditions are discussed